Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Dalfampridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dalfampridine SCHEMBL28757299 | 1.00 | MAPT (0.93) | — | |
| Dalfampridine SCHEMBL53483 | 0.96 | — | — | |
| Dalfampridine SCHEMBL1442620 | 0.96 | MAPT (1.00) | — | |
| Dalfampridine SCHEMBL28629661 | 0.93 | — | — | |
| Dalfampridine SCHEMBL8968143 | 0.93 | — | — | |
| Dalfampridine SCHEMBL28799379 | 0.93 | — | — | |
| Dalfampridine SCHEMBL31012422 | 0.93 | — | — | |
| Dalfampridine SCHEMBL3845825 | 0.93 | — | — | |
| Dalfampridine SCHEMBL7113651 | 0.93 | — | — | |
| Dalfampridine SCHEMBL28750367 | 0.93 | MAPT (0.93) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11994455-B2 | Analyte quantitation using Raman spectroscopy | ONDAVIA, INC. (US) | 2024-05-28 | — | — | US | disclosed |
| CN-108250795-B | A kind of disperse yellow dye composition | 浙江龙盛化工研究有限公司 | 2019-11-05 | — | — | CN | disclosed |
| CN-107603273-B | A kind of disperse yellow dye composition and its product | 浙江龙盛集团股份有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-109021616-A | A kind of disperse yellow dye composition, its product and application | 浙江龙盛集团股份有限公司 | 2018-12-18 | — | — | CN | disclosed |
| CN-108250795-A | A kind of disperse yellow dye composition | 浙江龙盛化工研究有限公司 | 2018-07-06 | — | — | CN | disclosed |
| CN-108102426-A | A kind of low temperature disperse yellow dye composition and preparation method thereof | 安徽凯奇化工科技股份有限公司 | 2018-06-01 | — | — | CN | disclosed |
| CN-107603273-A | A kind of disperse yellow dye composition and its product | 浙江龙盛集团股份有限公司 | 2018-01-19 | — | — | CN | disclosed |
| CN-103380176-B | Polycarbonate resin composition and molded article | 三菱化学株式会社 | 2016-10-26 | — | — | CN | disclosed |
| WO-2001007431-A2 | BENZOTHIOPHENE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-02-01 | — | — | WO | disclosed |
| CN-1230187-A | Bicyclic heteroaromatic compounds as protein tyrosine kinase inhibitors | GLAXO GROUP LTD (GB) | 1999-09-29 | — | — | CN | disclosed |