Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | OGA | O60502 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975974 | 0.81 | MAPK9 (0.49) | RAB9ANPC1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL8789026 | 0.81 | RAB9A (0.55) | RAB9ANPC1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL6138702 | 0.80 | RAB9A (0.56) | RAB9ANPC1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL12053329 | 0.79 | CYP3A4 (0.55) | RAB9ANPC1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL7502509 | 0.78 | RAB9A (0.53) | RAB9ANPC1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL7332440 | 0.78 | CYP3A4 (0.53) | RAB9ANPC1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL24580937 | 0.76 | CYP3A4 (0.52) | RAB9ANPC1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL7841290 | 0.76 | RAB9A (0.46) | RAB9ANPC1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL6975784 | 0.75 | RAB9A (0.51) | RAB9ANPC1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL6373806 | 0.75 | RAB9A (0.51) | RAB9ANPC1CYP3A4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207686-B1 | FOR THERAPY OF HYPERTENSION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |