Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987577 | 0.93 | NPC1 (0.48) | MAPK9HPGDPTGS1PTGS2MAPK1 | |
| SCHEMBL11161417 | 0.82 | MAPK9 (0.51) | MAPK9HPGDPTGS1PTGS2MAPK1 | |
| SCHEMBL7990464 | 0.81 | MAPK9 (0.54) | MAPK9HPGDPTGS1PTGS2MAPK1 | |
| SCHEMBL7987498 | 0.81 | RAB9A (0.48) | HPGDALDH1A1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL8035766 | 0.78 | PTGS1 (0.59) | MAPK9HPGDPTGS1PTGS2MAPK1 | |
| SCHEMBL4510613 | 0.78 | MAPK9 (0.56) | MAPK9HPGDPTGS1PTGS2MAPK1 | |
| SCHEMBL22722996 | 0.78 | MAPK9 (0.56) | MAPK9HPGDPTGS1PTGS2MAPK1 | |
| SCHEMBL1154990 | 0.78 | MAPK9 (0.56) | MAPK9HPGDPTGS1PTGS2MAPK1 | |
| SCHEMBL29785806 | 0.78 | MAPK9 (0.56) | MAPK9HPGDPTGS1PTGS2MAPK1 | |
| SCHEMBL7987319 | 0.78 | MAPK1 (0.50) | MAPK9HPGDPTGS1PTGS2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288248-B1 | REACTION OF ALLYL CHLORIDE AND PEROXIDE IN WATER AND METHANOL | Solvay (Société Anonyme) (BE) | 2001-09-11 | — | — | US | claimed |
| US-6207686-B1 | FOR THERAPY OF HYPERTENSION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |
| WO-1996015109-A1 | ENDOTHELIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-23 | — | — | WO | disclosed |