Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27332939 | 0.78 | CYP2C19 (0.67) | CYP2C19DPP4F2GBA1 | |
| SCHEMBL7418677 | 0.77 | SMN1; SMN2 (0.46) | LMNA | |
| SCHEMBL6528197 | 0.77 | DPP4 (0.46) | DPP4F2GBA1LMNA | |
| SCHEMBL2360079 | 0.77 | DPP4 (0.46) | DPP4F2GBA1LMNA | |
| SCHEMBL15232676 | 0.77 | DPP4 (0.50) | DPP4F2GBA1TAAR1LMNA | |
| SCHEMBL12305030 | 0.76 | CYP2C19 (0.44) | CYP2C19PSIP1TAAR1LMNA | |
| Hydrochloric Acid SCHEMBL3923326 | 0.76 | DPP4 (0.44) | DPP4F2GBA1LMNA | |
| Hydrochloric Acid SCHEMBL4574710 | 0.76 | DPP4 (0.44) | DPP4F2GBA1LMNA | |
| SCHEMBL3430220 | 0.75 | DPP4 (0.48) | DPP4F2GBA1 | |
| SCHEMBL11690239 | 0.74 | LMNA (0.50) | CYP2C19PSIP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109206360-A | Carbazole amide derivatives or its salt and its preparation method and application | 复旦大学 | 2019-01-15 | — | — | CN | disclosed |
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |