Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10452512 | 0.89 | LMNA (0.34) | LMNACYP2C19ALDH1A1KMT2AKDM4E | |
| SCHEMBL10452948 | 0.85 | PGK1 (0.41) | LMNACYP2C19ALDH1A1POLBKMT2A | |
| SCHEMBL9574373 | 0.80 | TSHR (0.39) | LMNACYP2C19ALDH1A1NPSR1PSIP1 | |
| SCHEMBL11435568 | 0.79 | ALDH1A1 (0.52) | LMNACYP2C19ALDH1A1POLBKMT2A | |
| SCHEMBL1557762 | 0.77 | ALDH1A1 (0.47) | LMNACYP2C19ALDH1A1POLBKMT2A | |
| SCHEMBL27962496 | 0.76 | POLB (0.46) | LMNACYP2C19ALDH1A1POLBKMT2A | |
| SCHEMBL5133327 | 0.76 | SRC (0.48) | LMNACYP2C19ALDH1A1KMT2ANPSR1 | |
| SCHEMBL12305030 | 0.76 | CYP2C19 (0.44) | LMNACYP2C19ALDH1A1POLBKMT2A | |
| SCHEMBL28254999 | 0.75 | SRC (0.62) | LMNACYP2C19ALDH1A1POLBKMT2A | |
| SCHEMBL332354 | 0.75 | ALDH1A1 (0.59) | LMNACYP2C19ALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053373-A | ELECTROPLATING OF NICKEL, COBALT, NICKEL-COBALT, NICKEL-IRON, COBALT-IRON AND NICKEL-IRON-COBALT DEPOSITS | M & T CHEMICALS INC. (US) | 1977-10-11 | — | — | US | claimed |