Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1326795 | 0.80 | ATM (0.56) | GAAALDH1A1TDP1ATML3MBTL1 | |
| SCHEMBL13807471 | 0.80 | ATM (0.56) | GAAALDH1A1TDP1ATML3MBTL1 | |
| SCHEMBL15428586 | 0.79 | ATM (0.55) | GAAALDH1A1TDP1ATML3MBTL1 | |
| SCHEMBL14013805 | 0.79 | ALDH1A1 (0.55) | GAAALDH1A1TDP1ATML3MBTL1 | |
| SCHEMBL552850 | 0.79 | ATM (0.55) | GAAALDH1A1TDP1ATML3MBTL1 | |
| SCHEMBL12528518 | 0.78 | GAA (0.50) | GAAALDH1A1TDP1ATML3MBTL1 | |
| SCHEMBL8568508 | 0.77 | SMN1; SMN2 (0.56) | GAAALDH1A1L3MBTL1POLBBAZ2B | |
| SCHEMBL1899061 | 0.76 | GAA (0.56) | GAAALDH1A1TDP1ATML3MBTL1 | |
| SCHEMBL13797533 | 0.76 | ALDH1A1 (0.52) | GAAALDH1A1TDP1ATML3MBTL1 | |
| SCHEMBL12293398 | 0.76 | ALDH1A1 (0.52) | GAAALDH1A1TDP1ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298747-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2011-03-23 | — | — | EP | disclosed |
| WO-2010001946-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | アステラス製薬株式会社 (JP) | 2010-01-07 | — | — | WO | disclosed |