SCHEMBL12528518

SCHEMBL12528518

CNC(=O)c1cc(Cl)cc(C)c1NC(=O)c1cc(C)nn1C(C)(C)C

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.50
ALDH1A1 P00352 2/20 0.50
TDP1 Q9NUW8 1/20 0.44
KMT2A Q03164 3/20 0.42
MEN1 O00255 1/20 0.42
ATM Q13315 3/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
POLB P06746 1/20 0.39
PKM P14618 1/20 0.39
F10 P00742 2/20 0.35
MAPT P10636 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
KDR P35968 3/20 0.34
RET P07949 2/20 0.34
FLT1 P17948 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12912046 0.87 PDE4B (0.38) GAAALDH1A1TDP1KMT2AMEN1
SCHEMBL12528525 0.83 NPC1 (0.53) GAAALDH1A1KMT2AMEN1F10
SCHEMBL12528501 0.82 KCNJ6 (0.36) KMT2AMEN1F10MAPTNPSR1
SCHEMBL12528467 0.82 MAPT (0.44) ALDH1A1KMT2AMEN1MAPTNPSR1
SCHEMBL12528301 0.79 KMT2A (0.59) ALDH1A1KMT2AMEN1F10MAPT
SCHEMBL12912053 0.79 NPC1 (0.39) GAAALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL7987940 0.78 GAA (0.57) GAAALDH1A1TDP1KMT2AMEN1
SCHEMBL12528610 0.78 KCNJ6 (0.42) F10KDRRET
SCHEMBL951117 0.78 PDE4B (0.37) GAAALDH1A1F10
SCHEMBL12528155 0.78 KMT2A (0.44) KMT2AMEN1L3MBTL1F10NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7968573-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-28 US disclosed
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME IKEGAMI HIROSHI 2011-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME ACHE, H1-2, H1-0 GAA 2045/4885ALDH1A1 238/4885TDP1 2997/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.