Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 19/20 | 0.50 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982228 | 0.89 | HSD11B1 (0.51) | HSD11B1HSD11B2 | |
| SCHEMBL7984554 | 0.89 | HSD11B1 (0.51) | HSD11B1HSD11B2 | |
| SCHEMBL7985076 | 0.89 | HSD11B1 (0.51) | HSD11B1HSD11B2 | |
| SCHEMBL7984121 | 0.89 | HSD11B1 (0.50) | HSD11B1 | |
| SCHEMBL7977548 | 0.88 | HSD11B1 (0.47) | HSD11B1 | |
| SCHEMBL7991818 | 0.86 | HSD11B1 (0.46) | HSD11B1HSD11B2SCN9A | |
| SCHEMBL12671005 | 0.86 | HSD11B1 (0.47) | HSD11B1HSD11B2 | |
| SCHEMBL7982107 | 0.84 | HSD11B1 (0.52) | HSD11B1HSD11B2 | |
| SCHEMBL7983813 | 0.83 | HSD11B1 (0.56) | HSD11B1HSD11B2 | |
| SCHEMBL7974537 | 0.82 | HSD11B1 (0.51) | HSD11B1HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001946-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | アステラス製薬株式会社 (JP) | 2010-01-07 | — | — | WO | disclosed |