Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7655743 | 0.99 | TP53 (0.42) | TP53MAPTRXFP1DRD2ADRA1A | |
| SCHEMBL7475928 | 0.94 | MAPT (0.39) | TP53MAPTDRD2ADRA1ADRD3 | |
| Hydrochloric Acid SCHEMBL7650535 | 0.93 | MAPT (0.39) | TP53MAPTDRD2ADRA1ADRD3 | |
| SCHEMBL7539113 | 0.92 | DRD3 (0.39) | TP53MAPTDRD2DRD3LMNA | |
| Hydrochloric Acid SCHEMBL7475220 | 0.91 | HTR2A (0.39) | TP53MAPTDRD2DRD3LMNA | |
| SCHEMBL7422472 | 0.90 | DRD2 (0.43) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7477971 | 0.89 | DRD2 (0.42) | DRD2DRD3 | |
| SCHEMBL7476712 | 0.89 | DRD2 (0.40) | MAPTDRD2ADRA1ADRD3NPSR1 | |
| Hydrochloric Acid SCHEMBL7481005 | 0.88 | DRD2 (0.39) | MAPTDRD2ADRA1ADRD3NPSR1 | |
| SCHEMBL7650118 | 0.87 | DRD2 (0.43) | DRD2ADRA1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221869-B1 | N-aminoalkyldibenzothiophenecarboxamides new dopamine receptor subtype specific ligands | NEUROGEN CORPORATION | 2001-04-24 | — | — | US | claimed |