Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 3/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988164 | 1.00 | CA1 (0.48) | CA1CA2POLBGAAMAPT | |
| SCHEMBL8450311 | 0.87 | CA1 (0.46) | CA1CA2POLBGAAMAPT | |
| SCHEMBL1513934 | 0.83 | MEN1 (0.41) | CA1CA2POLBGAAMAPT | |
| SCHEMBL7991854 | 0.83 | CA1 (0.56) | CA1CA2POLBGAAMAPT | |
| SCHEMBL7991858 | 0.83 | CA1 (0.56) | CA1CA2POLBGAAMAPT | |
| SCHEMBL30585894 | 0.82 | F7 (0.46) | MAPTKDM4E | |
| SCHEMBL7988025 | 0.81 | MAPT (0.53) | CA1CA2POLBGAAMAPT | |
| SCHEMBL7988028 | 0.81 | MAPT (0.53) | CA1CA2POLBGAAMAPT | |
| Alcohol SCHEMBL29092112 | 0.78 | ERN1 (0.63) | CA1CA2POLBGAAMAPT | |
| SCHEMBL9742944 | 0.77 | APP (0.51) | POLBGAAMAPTL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010024798-A1 | Biomimetic combinatorial synthesis | SHAIR MATTHEW D (US) | 2001-09-27 | — | — | US | disclosed |
| WO-1999064379-A2 | BIOMIMETIC COMBINATORIAL SYNTHESIS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1999-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010024798-A1 | Biomimetic combinatorial synthesis | COASY, BBOX1, CYP4B1 | CA1 3129/4885CA2 1678/4885POLB 927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.