SCHEMBL9742944

SCHEMBL9742944

CC/C=C/c1cc(O)ccc1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.51
ALDH1A1 P00352 3/20 0.50
MAPT P10636 3/20 0.50
KDM4E B2RXH2 2/20 0.50
MEN1 O00255 1/20 0.50
TP53 P04637 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
HPGD P15428 1/20 0.50
ALOX15 P16050 1/20 0.50
CYP2C19 P33261 1/20 0.50
KMT2A Q03164 1/20 0.50
HSD17B10 Q99714 1/20 0.50
GAA P10253 3/20 0.49
EGFR P00533 1/20 0.49
POLB P06746 1/20 0.49
PKM P14618 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
BACE1 P56817 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9742950 1.00 APP (0.51) APPALDH1A1MAPTKDM4EMEN1
SCHEMBL9743169 0.84 TYR (0.53) BACE1ALOX5
SCHEMBL9743164 0.84 TYR (0.53) BACE1ALOX5
SCHEMBL5802799 0.82 APP (0.50) APPALDH1A1MAPTKDM4EMEN1
SCHEMBL5802798 0.82 APP (0.50) APPALDH1A1MAPTKDM4EMEN1
SCHEMBL2734712 0.82 ALDH1A1 (0.52) APPALDH1A1MAPTKDM4EMEN1
SCHEMBL28819473 0.79 APP (0.48) APPALDH1A1MAPTKDM4EMEN1
SCHEMBL28819474 0.79 APP (0.48) APPALDH1A1MAPTKDM4EMEN1
SCHEMBL30792609 0.79 APP (0.48) APPALDH1A1MAPTKDM4EMEN1
SCHEMBL7991883 0.78 ERN1 (0.59) APPALDH1A1MAPTKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5087548-A POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION JAPAN SYNTHETIC RUBBER CO., INC. (JP) 1992-02-11 US disclosed
EP-0227487-A2 Positive type radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1987-07-01 EP disclosed