Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 17/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1417724 | 0.86 | AR (0.35) | HSD11B1 | |
| SCHEMBL7987997 | 0.86 | HSD11B1 (0.51) | HSD11B1 | |
| SCHEMBL1417933 | 0.86 | HSD11B1 (0.34) | HSD11B1 | |
| SCHEMBL7974537 | 0.82 | HSD11B1 (0.51) | HSD11B1 | |
| SCHEMBL7979290 | 0.77 | HSD11B1 (0.52) | HSD11B1 | |
| SCHEMBL7983827 | 0.76 | HSD11B1 (0.51) | HSD11B1 | |
| SCHEMBL7985222 | 0.76 | GLA (0.47) | GLAPOLBGAATSHRHSD11B1 | |
| SCHEMBL7988226 | 0.76 | GLA (0.47) | GLAPOLBGAATSHRHSD11B1 | |
| SCHEMBL7991812 | 0.75 | HSD11B1 (0.52) | HSD11B1 | |
| SCHEMBL7968411 | 0.75 | HSD11B1 (0.52) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001946-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | アステラス製薬株式会社 (JP) | 2010-01-07 | — | — | WO | disclosed |