Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 18/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988226 | 1.00 | GLA (0.47) | GLAPOLBGAATSHRHSD11B1 | |
| SCHEMBL12670873 | 0.81 | HSD11B1 (0.42) | HSD11B1 | |
| SCHEMBL1417560 | 0.81 | HSD11B1 (0.42) | HSD11B1 | |
| SCHEMBL7991381 | 0.81 | HSD11B1 (0.69) | HSD11B1 | |
| SCHEMBL1417665 | 0.81 | HSD11B1 (0.69) | HSD11B1 | |
| SCHEMBL1417836 | 0.81 | HSD11B1 (0.69) | HSD11B1 | |
| SCHEMBL7980917 | 0.78 | GLA (0.49) | GLAPOLBGAATSHRHSD11B1 | |
| SCHEMBL7988166 | 0.76 | GLA (0.36) | GLAPOLBGAATSHRHSD11B1 | |
| SCHEMBL7979418 | 0.71 | HSD11B1 (0.50) | HSD11B1 | |
| SCHEMBL7979290 | 0.70 | HSD11B1 (0.52) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001946-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | アステラス製薬株式会社 (JP) | 2010-01-07 | — | — | WO | disclosed |