Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 3/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977296 | 0.84 | PTGDR2 (0.43) | PTGDR2KDM4EHRH1 | |
| SCHEMBL8809016 | 0.82 | HRH4 (0.30) | HRH4HRH3 | |
| SCHEMBL4379614 | 0.82 | BRD4 (0.33) | BRD4PTGDR2KDM4EHRH1 | |
| SCHEMBL4376051 | 0.78 | POLB (0.33) | PTGDR2KDM4E | |
| SCHEMBL28986115 | 0.76 | GAA (0.46) | AOC3TACR1 | |
| SCHEMBL7991354 | 0.75 | — | — | |
| SCHEMBL7975009 | 0.74 | HPGD (0.56) | HRH2HRH4TACR1HRH1HRH3 | |
| SCHEMBL7975013 | 0.74 | HPGD (0.56) | HRH2HRH4TACR1HRH1HRH3 | |
| SCHEMBL7975015 | 0.74 | HPGD (0.56) | HRH2HRH4TACR1HRH1HRH3 | |
| SCHEMBL4382548 | 0.73 | NPC1 (0.47) | HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | claimed |