Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GLP1R | P43220 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 10/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4379243 | 0.90 | PTGDR2 (0.36) | PTGDR2ALDH1A1CYP3A4TSHRCYP2C19 | |
| SCHEMBL7433406 | 0.85 | PTGDR2 (0.37) | PTGDR2ALDH1A1CYP3A4TSHRCYP2C19 | |
| Hydrochloric Acid SCHEMBL7428983 | 0.84 | PTGDR2 (0.36) | PTGDR2ALDH1A1CYP3A4TSHRCYP2C19 | |
| SCHEMBL7988259 | 0.84 | AOC3 (0.35) | PTGDR2KDM4EHRH1 | |
| SCHEMBL4379614 | 0.82 | BRD4 (0.33) | PTGDR2ALDH1A1CYP3A4TSHRCYP2C19 | |
| SCHEMBL4376051 | 0.81 | POLB (0.33) | PTGDR2ALDH1A1CYP3A4TSHRCYP2C19 | |
| SCHEMBL9119383 | 0.81 | CYP19A1 (0.43) | HTR2AHRH1 | |
| SCHEMBL7286799 | 0.80 | SIGMAR1 (0.38) | PTGDR2TSHRLMNAL3MBTL1HTR2A | |
| SCHEMBL7285523 | 0.80 | CYP19A1 (0.40) | PTGDR2ALDH1A1LMNAHTR2AHRH1 | |
| SCHEMBL9122156 | 0.80 | HRH1 (0.42) | HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | claimed |