SCHEMBL8809016

SCHEMBL8809016

CCC(C)CN(CCCc1c[nH]cn1)C(=O)O

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7988259 0.82 AOC3 (0.35) HRH4HRH3
SCHEMBL4379243 0.80 PTGDR2 (0.36)
SCHEMBL7989091 0.78
SCHEMBL7991354 0.78
SCHEMBL7977296 0.75 PTGDR2 (0.43)
SCHEMBL8684896 0.74 HTR1A (0.36)
SCHEMBL15573739 0.74 ALDH1A1 (0.31) HRH4HRH3
SCHEMBL4384698 0.72
SCHEMBL4379614 0.72 BRD4 (0.33)
SCHEMBL16822333 0.72 HDAC1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0760811-A1 IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H 3? (ANT)AGONISTS INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 1997-03-12 EP disclosed