Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.58 |
| ▸ | CES1 | P23141 | 1/20 | 0.58 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988285 | 1.00 | CES2 (0.58) | CES2CES1PARP1ALDH1A1TSHR | |
| SCHEMBL2007841 | 0.86 | CES2 (0.69) | CES2CES1PARP1ALDH1A1TSHR | |
| SCHEMBL7988180 | 0.83 | CES2 (0.53) | CES2CES1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7988181 | 0.83 | CES2 (0.53) | CES2CES1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1339638 | 0.82 | CES2 (0.51) | CES2CES1PARP1ALDH1A1TSHR | |
| SCHEMBL29697823 | 0.82 | CES2 (0.51) | CES2CES1PARP1ALDH1A1TSHR | |
| SCHEMBL1339641 | 0.82 | CES2 (0.51) | CES2CES1PARP1ALDH1A1TSHR | |
| SCHEMBL19663921 | 0.81 | ALDH1A1 (0.61) | CES2CES1ALDH1A1TSHRNPC1 | |
| SCHEMBL1968821 | 0.81 | ALDH1A1 (0.61) | CES2CES1ALDH1A1TSHRNPC1 | |
| SCHEMBL1126729 | 0.81 | ALDH1A1 (0.61) | CES2CES1ALDH1A1TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |