Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGDS | O60760 | 2/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975140 | 0.91 | ESR2 (0.44) | ESR2MAPTHPGDSNR1H2MAPK1 | |
| SCHEMBL7986367 | 0.91 | ESR2 (0.47) | ESR2MAPTHPGDSNR1H2MAPK1 | |
| SCHEMBL30171269 | 0.87 | ESR2 (0.48) | ESR2MAPTHPGDSNR1H2MAPK1 | |
| SCHEMBL1881390 | 0.86 | ESR2 (0.47) | ESR2MAPTHPGDSNR1H2MAPK1 | |
| SCHEMBL5777653 | 0.84 | ESR2 (0.46) | ESR2MAPTHPGDSNR1H2MAPK1 | |
| SCHEMBL20792551 | 0.82 | MAPT (0.53) | ESR2MAPTHPGDSNR1H2MAPK1 | |
| SCHEMBL16217166 | 0.81 | ESR2 (0.52) | ESR2MAPTHPGDSNR1H2MAPK1 | |
| SCHEMBL17868214 | 0.80 | HPGDS (0.43) | ESR2MAPTHPGDSNR1H2MAPK1 | |
| SCHEMBL17327937 | 0.80 | ESR2 (0.51) | ESR2MAPTHPGDSNR1H2MAPK1 | |
| SCHEMBL16220602 | 0.80 | ESR2 (0.51) | ESR2MAPTHPGDSNR1H2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |