Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988322 | 0.91 | ESR2 (0.47) | ESR2HPGDSMAPTNR1H2ADORA1 | |
| SCHEMBL7986367 | 0.86 | ESR2 (0.47) | ESR2HPGDSMAPTNR1H2ADORA1 | |
| SCHEMBL30171269 | 0.83 | ESR2 (0.48) | ESR2HPGDSMAPTNR1H2ADORA1 | |
| SCHEMBL1881390 | 0.82 | ESR2 (0.47) | ESR2HPGDSMAPTNR1H2ADORA1 | |
| SCHEMBL5777653 | 0.80 | ESR2 (0.46) | ESR2HPGDSMAPTNR1H2SLC34A1 | |
| SCHEMBL20792551 | 0.78 | MAPT (0.53) | ESR2HPGDSMAPTNR1H2SLC34A1 | |
| SCHEMBL7988759 | 0.78 | KMT2A (0.50) | ESR2MAPTNR1H2ADORA1SMN1; SMN2 | |
| SCHEMBL7992630 | 0.78 | ADORA1 (0.46) | ESR2MAPTNR1H2ADORA1MAPK1 | |
| SCHEMBL16217166 | 0.78 | ESR2 (0.52) | ESR2HPGDSMAPTNR1H2ADORA1 | |
| SCHEMBL7989185 | 0.77 | ESR2 (0.50) | ESR2MAPTNR1H2ADORA1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |