Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 7/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.41 |
| ▸ | PARN | O95453 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974262 | 0.89 | ALDH1A1 (0.45) | ALDH1A1CYP11B1CYP11B2HPGDTSHR | |
| SCHEMBL7989504 | 0.88 | GRIN1 (0.41) | ALDH1A1HPGDTSHRCNOT7PARN | |
| SCHEMBL7987676 | 0.88 | SMN1; SMN2 (0.49) | HTTSMN1; SMN2CNOT7PARN | |
| SCHEMBL7984366 | 0.88 | CNOT7 (0.53) | ALDH1A1HPGDSMN1; SMN2CNOT7PARN | |
| Hydrochloric Acid SCHEMBL7987808 | 0.87 | SMN1; SMN2 (0.48) | HTTSMN1; SMN2CNOT7PARN | |
| SCHEMBL7988665 | 0.87 | ALDH1A1 (0.44) | ALDH1A1CYP11B1CYP11B2HPGDTSHR | |
| Hydrochloric Acid SCHEMBL7992068 | 0.86 | CNOT7 (0.52) | ALDH1A1HPGDSMN1; SMN2CNOT7PARN | |
| SCHEMBL7988039 | 0.86 | CNOT7 (0.41) | ALDH1A1CYP11B1CYP11B2HPGDTSHR | |
| SCHEMBL7986366 | 0.86 | TP53 (0.51) | LMNAMAPTTP53 | |
| SCHEMBL7992187 | 0.86 | ALDH1A1 (0.43) | ALDH1A1CYP11B1CYP11B2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |