Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 3/20 | 0.41 |
| ▸ | PARN | O95453 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7988145 | 0.99 | CNOT7 (0.40) | CNOT7PARNLMNASMN1; SMN2CYP11B1 | |
| SCHEMBL7985516 | 0.89 | CNOT7 (0.40) | CNOT7PARNLMNASMN1; SMN2CYP11B2 | |
| SCHEMBL7984366 | 0.89 | CNOT7 (0.53) | CNOT7PARNSMN1; SMN2BRD4KMT2A | |
| Hydrochloric Acid SCHEMBL7988733 | 0.88 | CNOT7 (0.40) | CNOT7PARNLMNASMN1; SMN2CYP11B2 | |
| Hydrochloric Acid SCHEMBL7992068 | 0.88 | CNOT7 (0.52) | CNOT7PARNSMN1; SMN2BRD4KMT2A | |
| SCHEMBL7987439 | 0.88 | CNOT7 (0.43) | CNOT7PARNLMNASMN1; SMN2CYP11B1 | |
| SCHEMBL7991686 | 0.87 | ABCC8 (0.48) | CNOT7PARNLMNASMN1; SMN2CYP11B1 | |
| Hydrochloric Acid SCHEMBL7985467 | 0.86 | ABCC8 (0.47) | CNOT7PARNLMNASMN1; SMN2CYP11B1 | |
| SCHEMBL7988359 | 0.86 | ALDH1A1 (0.44) | CNOT7PARNLMNASMN1; SMN2CYP11B1 | |
| SCHEMBL7989379 | 0.86 | CNOT7 (0.41) | CNOT7PARNLMNASMN1; SMN2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |