Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 1/20 | 0.46 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.46 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984206 | 0.91 | HPGD (0.46) | PDE1APDE1BPDE1CHPGDALDH1A1 | |
| SCHEMBL7988531 | 0.89 | ALDH1A1 (0.44) | PDE1APDE1BPDE1CHPGDALDH1A1 | |
| SCHEMBL7988657 | 0.88 | HPGD (0.45) | HPGDALDH1A1SMN1; SMN2KMT2AHCAR2 | |
| SCHEMBL7991723 | 0.87 | SMN1; SMN2 (0.49) | HPGDALDH1A1SMN1; SMN2KMT2AHCAR2 | |
| SCHEMBL7988953 | 0.87 | HPGD (0.45) | HPGDALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL7989405 | 0.87 | SMN1; SMN2 (0.57) | HPGDALDH1A1SMN1; SMN2KMT2AHCAR2 | |
| SCHEMBL7989507 | 0.86 | HPGD (0.46) | HPGDALDH1A1SMN1; SMN2KMT2AHCAR2 | |
| SCHEMBL7984130 | 0.85 | GAA (0.52) | HPGDALDH1A1SMN1; SMN2KMT2AHCAR2 | |
| SCHEMBL7988487 | 0.83 | PDE1A (0.46) | PDE1APDE1BPDE1CHPGDALDH1A1 | |
| SCHEMBL7985859 | 0.82 | CNOT7 (0.49) | HPGDALDH1A1SMN1; SMN2KMT2AHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |