Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4435902 | 0.88 | GAA (0.54) | GAATSHRMAPTLMNAPOLB | |
| SCHEMBL11701711 | 0.88 | MAPT (0.64) | GAATSHRMAPTLMNAPOLB | |
| SCHEMBL27929357 | 0.88 | KMT2A (0.60) | GAATSHRMAPTLMNAPOLB | |
| SCHEMBL11701052 | 0.85 | MAPT (0.60) | GAATSHRMAPTLMNAPOLB | |
| SCHEMBL948187 | 0.84 | GAA (0.62) | GAATSHRMAPTLMNAPOLB | |
| SCHEMBL15242477 | 0.84 | PLA2G4B (0.59) | TSHRMAPTLMNAPOLBNPSR1 | |
| 3-Methylbutanoic Acid SCHEMBL11701670 | 0.84 | MAPT (0.57) | GAATSHRMAPTLMNAPOLB | |
| SCHEMBL5402453 | 0.82 | ADRB2 (0.59) | MAPTADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL948679 | 0.81 | KMT2A (0.58) | GAAMAPTLMNANPSR1KMT2A | |
| SCHEMBL16358433 | 0.81 | ADRB2 (0.59) | GAAMAPTLMNAPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001029014-A1 | ISOTHIAZOLE-5-CARBOXYLIC ESTERS AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-04-26 | — | — | WO | disclosed |