Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27929357 | 0.90 | KMT2A (0.60) | KMT2AMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL7989426 | 0.89 | MAPT (0.58) | KMT2ACA12CA1CA2ESR1 | |
| SCHEMBL25936562 | 0.87 | MAPT (0.53) | KMT2ACA12CA1CA2ESR1 | |
| SCHEMBL27536527 | 0.87 | MAPT (0.60) | KMT2ACA12CA1CA2ESR1 | |
| SCHEMBL948187 | 0.87 | GAA (0.62) | KMT2AMAPTALDH1A1HPGDGAA | |
| SCHEMBL5167985 | 0.86 | CA12 (0.63) | KMT2ACA12CA1CA2ESR1 | |
| SCHEMBL11339159 | 0.86 | MAPT (0.55) | KMT2ACA12CA1CA2ESR1 | |
| SCHEMBL24214161 | 0.85 | MAPT (0.54) | KMT2ACA12CA1CA2ESR1 | |
| SCHEMBL11347526 | 0.84 | GAA (0.53) | KMT2ACA12CA1CA2ESR1 | |
| SCHEMBL76052 | 0.84 | ALDH1A1 (0.66) | CA12CA1CA2ESR1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111825601-A | Method for continuously preparing pimavanserin by using microchannel reactor | 杭州珠联医药科技有限公司 | 2020-10-27 | — | — | CN | claimed |
| EP-2958950-B1 | AN IMPROVED MAGNESIUM DICHLORIDE SUPPORTED TITANIUM CATALYST COMPOSITION FOR POLYOLEFIN POLYMERIZATION | RELIANCE INDUSTRIES LTD (IN) | 2019-09-11 | — | — | EP | claimed |
| US-20160002372-A1 | Magnesium Dichloride Supported Titanium Catalyst Composition for Polyolefin Polymerization | RELIANCE INDUSTRIES LIMITED (IN) | 2016-01-07 | — | — | US | claimed |
| EP-2958950-A2 | AN IMPROVED MAGNESIUM DICHLORIDE SUPPORTED TITANIUM CATALYST COMPOSITION FOR POLYOLEFIN POLYMERIZATION | Reliance Industries Limited (IN) | 2015-12-30 | — | — | EP | claimed |
| WO-2014128715-A2 | AN IMPROVED MAGNESIUM DICHLORIDE SUPPORTED TITANIUM CATALYST COMPOSITION FOR POLYOLEFIN POLYMERIZATION | RELIANCE INDUSTRIES LIMITED (IN) | 2014-08-28 | — | — | WO | claimed |
| US-11440884-B2 | Compounds, salts thereof and methods for treatment of diseases | ACADIA PHARMACEUTICALS INC. (US) | 2022-09-13 | — | — | US | disclosed |
| US-20210122713-A1 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2021-04-29 | — | — | US | disclosed |
| CN-111825601-A | Method for continuously preparing pimavanserin by using microchannel reactor | 杭州珠联医药科技有限公司 | 2020-10-27 | — | — | CN | disclosed |
| EP-3672960-A2 | COMPOUNDS, SALTS THEREOF AND THEIR USE FOR THE TREATMENT OF DISEASES | Acadia Pharmaceuticals Inc. (US) | 2020-07-01 | — | — | EP | disclosed |
| EP-2958950-B1 | AN IMPROVED MAGNESIUM DICHLORIDE SUPPORTED TITANIUM CATALYST COMPOSITION FOR POLYOLEFIN POLYMERIZATION | RELIANCE INDUSTRIES LTD (IN) | 2019-09-11 | — | — | EP | disclosed |
| WO-2019040104-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2019-02-28 | — | — | WO | disclosed |
| US-20160002372-A1 | Magnesium Dichloride Supported Titanium Catalyst Composition for Polyolefin Polymerization | RELIANCE INDUSTRIES LIMITED (IN) | 2016-01-07 | — | — | US | disclosed |
| EP-2958950-A2 | AN IMPROVED MAGNESIUM DICHLORIDE SUPPORTED TITANIUM CATALYST COMPOSITION FOR POLYOLEFIN POLYMERIZATION | Reliance Industries Limited (IN) | 2015-12-30 | — | — | EP | disclosed |
| WO-2014128715-A2 | AN IMPROVED MAGNESIUM DICHLORIDE SUPPORTED TITANIUM CATALYST COMPOSITION FOR POLYOLEFIN POLYMERIZATION | RELIANCE INDUSTRIES LIMITED (IN) | 2014-08-28 | — | — | WO | disclosed |
| EP-2257576-B1 | A PROCESS FOR THE SYNTHESIS OF ALPHA-OLEFIN POLYMERIZATION PROCATALYSTS | RELIANCE IND LTD (IN) | 2013-02-20 | — | — | EP | disclosed |
| US-8283424-B2 | Process for the synthesis of alpha-olefin polymerization procatalysts | RELIANCE INDUSTRIES LIMITED (IN) | 2012-10-09 | — | — | US | disclosed |
| US-20110015355-A1 | PROCESS FOR THE SYNTHESIS OF ALPHA-OLEFIN POLYMERIZATION PROCATALYSTS | RELIANCE INDUSTRIES LIMITED (IN) | 2011-01-20 | — | — | US | disclosed |
| EP-2257576-A2 | A PROCESS FOR THE SYNTHESIS OF ALPHA-OLEFIN POLYMERIZATION PROCATALYSTS | Reliance Industries Limited (IN) | 2010-12-08 | — | — | EP | disclosed |
| WO-2009116057-A2 | A PROCESS FOR THE SYNTHESIS OF ALPHA-OLEFIN POLYMERIZATION PROCATALYSTS | RELIANCE INDUSTRIES LIMITED (IN) | 2009-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11440884-B2 | Compounds, salts thereof and methods for treatment of diseases | SLC10A1, VHL, CYP11B2 | KMT2A 3216/4885CA12 233/4885CA1 872/4885 |
| US-20210122713-A1 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | SLC10A1, VHL, CYP11B2 | KMT2A 3216/4885CA12 233/4885CA1 872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.