SCHEMBL7988628

SCHEMBL7988628

CC(C)(C)c1ccc(Oc2cc(C(=O)O)c3c(C(=O)O)ccc4c5c(Oc6ccc(C(C)(C)C)cc6)cc(C(=O)O)c6c(C(=O)O)ccc(c2c34)c65)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DHODH Q02127 1/20 0.46
▸ XDH P47989 1/20 0.45
▸ AKR1C3 P42330 1/20 0.44
▸ AKR1C2 P52895 1/20 0.44
▸ KDM4E B2RXH2 2/20 0.40
▸ HSD17B10 Q99714 2/20 0.40
▸ MAPT P10636 2/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ POLB P06746 1/20 0.40
▸ CYP2D6 P10635 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ ATM Q13315 1/20 0.40
▸ ICAM1 P05362 1/20 0.40
▸ SELE P16581 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ FGFR2 P21802 1/20 0.39
▸ TDP1 Q9NUW8 2/20 0.39
▸ ALDH1A1 P00352 2/20 0.39
▸ HPGD P15428 2/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28647685 0.91 DHODH (0.43) DHODHXDHAKR1C3AKR1C2KDM4E
SCHEMBL28899372 0.90 ICAM1 (0.42) DHODHXDHAKR1C3AKR1C2KDM4E
SCHEMBL17923575 0.88 XDH (0.46) DHODHXDHAKR1C3AKR1C2KDM4E
SCHEMBL28638964 0.87 ALDH1A1 (0.47) DHODHXDHAKR1C3AKR1C2MAPT
SCHEMBL17929969 0.87 ICAM1 (0.40) DHODHXDHAKR1C3AKR1C2MAPT
SCHEMBL8210928 0.83 CYP1A2 (0.44) DHODHXDHAKR1C3KDM4EPOLB
SCHEMBL17923574 0.80 ALDH1A1 (0.42) KDM4EHSD17B10MEN1KMT2AATM
SCHEMBL28656552 0.80 TSHR (0.37) DHODHXDHKDM4EHSD17B10POLB
SCHEMBL17923571 0.79 XDH (0.40) DHODHXDHAKR1C3AKR1C2KDM4E
SCHEMBL6512030 0.75 NR1H4 (0.39) KDM4EMAPTMEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11322690-B2 Light harvesting array FLUROSOL INDUSTRIES PTY LTD (AU) 2022-05-03 — — US disclosed
US-20160211453-A1 LIGHT HARVESTING ARRAY FLUROSOL INDUSTRIES PTY LTD. (AU) 2016-07-21 — — US disclosed
US-6326494-B1 LASER DYES BASF AKTIENGESELLSCHAFT (DE) 2001-12-04 — — US disclosed
US-6143905-A REACTING 1,7-DIBROMOPERYLENE-3,4,9,10-TETRACARBOXYLIC DIANHYDRIDE OR TETRACARBOXYLIC ACID IN PRESENCE OF APROTIC SOLVENT WITH A PRIMARY AMINE TO FORM DIIMIDE, REACTING DIIMIDE WITH AROMATIC ALOCHOL OR THIOL, AND HYDROLYZING BASF AKTIENGESELLSCHAFT (DE) 2000-11-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160211453-A1 LIGHT HARVESTING ARRAY SUN2, ALG8, GNE DHODH 293/4885XDH 1798/4885AKR1C3 1993/4885
US-11322690-B2 Light harvesting array SUN2, ALG8, GNE DHODH 293/4885XDH 1798/4885AKR1C3 1993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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