Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PARN | O95453 | 1/20 | 0.42 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.42 |
| ▸ | YTHDC1 | Q96MU7 | 3/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991727 | 0.89 | SMN1; SMN2 (0.49) | SMN1; SMN2GLAHTTUBE2NL3MBTL1 | |
| SCHEMBL7985640 | 0.89 | CNOT7 (0.53) | SMN1; SMN2PARNCNOT7 | |
| Hydrochloric Acid SCHEMBL7987619 | 0.88 | CNOT7 (0.52) | SMN1; SMN2PARNCNOT7 | |
| SCHEMBL7988534 | 0.87 | TAAR1 (0.41) | PARNCNOT7TAAR1EGFR | |
| SCHEMBL7992187 | 0.87 | ALDH1A1 (0.43) | SMN1; SMN2HTTPARNCNOT7TAAR1 | |
| SCHEMBL7984758 | 0.87 | SMN1; SMN2 (0.51) | SMN1; SMN2GLAHTTUBE2NL3MBTL1 | |
| SCHEMBL7987676 | 0.85 | SMN1; SMN2 (0.49) | SMN1; SMN2GLAHTTUBE2NL3MBTL1 | |
| SCHEMBL7985278 | 0.85 | TP53 (0.50) | YTHDC1TAAR1 | |
| Hydrochloric Acid SCHEMBL7987808 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2GLAHTTUBE2NL3MBTL1 | |
| SCHEMBL7988672 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2GLAHTTUBE2NL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |