Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.40 |
| ▸ | PARN | O95453 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 4/20 | 0.37 |
| ▸ | PDE1A | P54750 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.37 |
| ▸ | DBH | P09172 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988487 | 0.89 | PDE1A (0.46) | ROCK2ROCK1CNOT7PARNGRIN1 | |
| SCHEMBL7988676 | 0.87 | SMN1; SMN2 (0.47) | TAAR1CNOT7PARNEGFR | |
| SCHEMBL7992187 | 0.87 | ALDH1A1 (0.43) | TAAR1CNOT7PARNIDO1 | |
| SCHEMBL7984210 | 0.87 | GRIN1 (0.43) | ROCK2ROCK1CNOT7PARNGRIN1 | |
| SCHEMBL7974307 | 0.87 | CNOT7 (0.40) | TAAR1CNOT7PARNIDO1 | |
| SCHEMBL7985640 | 0.87 | CNOT7 (0.53) | CNOT7PARN | |
| Hydrochloric Acid SCHEMBL7987619 | 0.85 | CNOT7 (0.52) | CNOT7PARN | |
| SCHEMBL7989504 | 0.85 | GRIN1 (0.41) | ROCK2ROCK1CNOT7PARNGRIN1 | |
| SCHEMBL7985278 | 0.85 | TP53 (0.50) | TAAR1ROCK2ROCK1 | |
| SCHEMBL7988531 | 0.83 | ALDH1A1 (0.44) | TAAR1ROCK2ROCK1GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |