Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 14/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | WNT3A | P56704 | 1/20 | 0.55 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24695901 | 0.86 | GSK3B (0.72) | GSK3BWNT3AGRM5 | |
| SCHEMBL30388073 | 0.85 | WNT3A (0.77) | NR1I2GSK3BWNT3A | |
| SCHEMBL20604148 | 0.85 | WNT3A (0.77) | NR1I2GSK3BWNT3A | |
| SCHEMBL24694838 | 0.82 | GSK3B (0.58) | NR1I2GSK3BWNT3A | |
| SCHEMBL7996185 | 0.80 | GRM5 (0.61) | NR1I2GRM5 | |
| SCHEMBL3405207 | 0.79 | GRM5 (0.67) | GRM5 | |
| SCHEMBL20604169 | 0.78 | GRM5 (0.58) | GSK3BWNT3AGRM5 | |
| SCHEMBL30387819 | 0.78 | GRM5 (0.58) | GSK3BWNT3AGRM5 | |
| SCHEMBL17454344 | 0.77 | MAPT (0.61) | NR1I2RXFP1 | |
| SCHEMBL3406092 | 0.77 | HTT (0.61) | NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009115486-A1 | TRIAZOLE AMIDE DERIVATIVES FOR USE IN THERAPY | GLAXO GROUP LIMITED (GB) | 2009-09-24 | — | — | WO | disclosed |