Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | UBE2M | P61081 | 2/20 | 0.51 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.51 |
| ▸ | CCR3 | P51677 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7926185 | 0.86 | CCR3 (0.59) | UBE2MDCUN1D1CCR3MAPTTACR1 | |
| SCHEMBL7932667 | 0.83 | LMNA (0.47) | FAAHTSHRCCR3ALDH1A1L3MBTL1 | |
| SCHEMBL7934769 | 0.81 | CCR3 (0.56) | CCR3TACR1 | |
| SCHEMBL7938443 | 0.80 | CCR3 (0.72) | CCR3TACR1 | |
| SCHEMBL7932645 | 0.79 | CCR3 (0.56) | CCR3TACR1 | |
| SCHEMBL7938403 | 0.79 | CCR3 (0.59) | CCR3TACR1 | |
| SCHEMBL7986617 | 0.79 | CCR3 (0.71) | CCR3TACR1 | |
| SCHEMBL7992865 | 0.77 | CCR3 (0.56) | CCR3TACR1 | |
| SCHEMBL7935026 | 0.77 | CCR3 (0.58) | TSHRCCR3ALDH1A1TP53LMNA | |
| SCHEMBL7934845 | 0.77 | CCR3 (0.70) | CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191135-B1 | Neurokinin antagonists | BOEHRINGER INGELHEIM KG (DE) | 2001-02-20 | — | — | US | claimed |
| US-6191135-B1 | Neurokinin antagonists | BOEHRINGER INGELHEIM KG (DE) | 2001-02-20 | — | — | US | disclosed |
| US-5985881-A | TREATMENT AND PREVENTION OF RESPIRATORY DISORDERS, INFLAMMATORY EYE DISEASES, INFLAMMATORY SKIN DISEASES, INTESTINAL DISORDERS, OTHER INFLAMMATORY DISEASES | BOEHRINGER INGELHEIM KG (DE) | 1999-11-16 | — | — | US | disclosed |