Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984893 | 0.94 | KDM4E (0.50) | GAAKDM4EHPGDKMT2ANPSR1 | |
| SCHEMBL7974583 | 0.90 | GAA (0.59) | GAAHPGDALDH1A1KMT2ANPSR1 | |
| SCHEMBL7985844 | 0.87 | GAA (0.52) | GAAKDM4EHPGDALDH1A1MAPT | |
| SCHEMBL7974613 | 0.86 | CNOT7 (0.49) | KDM4EHPGDALDH1A1KMT2AHTT | |
| SCHEMBL7974016 | 0.86 | GAA (0.56) | GAAHPGDALDH1A1MAPTKMT2A | |
| SCHEMBL7988550 | 0.85 | ALDH1A1 (0.44) | KDM4EHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL7984403 | 0.85 | CNOT7 (0.47) | KDM4EHPGDALDH1A1KMT2ALMNA | |
| SCHEMBL7988580 | 0.85 | ALDH1A1 (0.44) | GAAKDM4EHPGDALDH1A1MAPT | |
| SCHEMBL7984680 | 0.85 | CNOT7 (0.43) | KDM4EHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL7989011 | 0.84 | KDM4E (0.48) | GAAKDM4EHPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |