Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CNOT7 | Q9UIV1 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984902 | 0.94 | CNOT7 (0.49) | KDM4ECNOT7HPGDALDH1A1MAPT | |
| SCHEMBL7974586 | 0.90 | GAA (0.52) | CNOT7MAPTGAAPIN1TP53 | |
| SCHEMBL7985852 | 0.87 | TP53 (0.52) | MAPTGAALMNATP53 | |
| SCHEMBL7974620 | 0.86 | CNOT7 (0.58) | KDM4ECNOT7ALDH1A1LMNAMAPK1 | |
| SCHEMBL7974021 | 0.86 | TP53 (0.51) | CNOT7ALDH1A1MAPTGAAUSP2 | |
| SCHEMBL7984686 | 0.85 | CNOT7 (0.50) | KDM4ECNOT7ALDH1A1PIN1LMNA | |
| SCHEMBL7988553 | 0.85 | CNOT7 (0.50) | CNOT7ALDH1A1PIN1 | |
| SCHEMBL7984409 | 0.85 | CNOT7 (0.53) | KDM4ECNOT7ALDH1A1LMNAMAPK1 | |
| SCHEMBL7988586 | 0.85 | CNOT7 (0.50) | KDM4ECNOT7HPGDALDH1A1MAPT | |
| SCHEMBL7989007 | 0.84 | GAA (0.50) | KDM4EHPGDALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |