Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | PARN | O95453 | 1/20 | 0.46 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985852 | 0.95 | TP53 (0.52) | GAATP53RXFP1MAPT | |
| SCHEMBL7974021 | 0.94 | TP53 (0.51) | GAATP53RXFP1PARNCNOT7 | |
| SCHEMBL7991877 | 0.92 | P2RX7 (0.47) | GAATP53RXFP1MAPTP2RX7 | |
| SCHEMBL7991545 | 0.92 | TSHR (0.48) | GAATP53RXFP1MAPTPIN1 | |
| SCHEMBL7985350 | 0.92 | GAA (0.48) | GAATP53RXFP1PARNCNOT7 | |
| SCHEMBL7985381 | 0.91 | HPGD (0.48) | GAATP53RXFP1MAPTP2RX7 | |
| SCHEMBL7974195 | 0.91 | GAA (0.48) | GAATP53RXFP1MAPTP2RX7 | |
| SCHEMBL7974409 | 0.91 | PARN (0.45) | GAATP53PARNCNOT7MAPT | |
| SCHEMBL7985580 | 0.90 | HPGD (0.49) | GAATP53RXFP1P2RX7 | |
| SCHEMBL7974096 | 0.90 | TP53 (0.48) | GAATP53RXFP1MAPTP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |