Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | AVPR1B | P47901 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989520 | 0.92 | SLC2A1 (0.51) | SIRT2SIRT1SLC2A1SIRT3TARBP2 | |
| SCHEMBL7989738 | 0.87 | PARP1 (0.45) | ACHEAVPR1BALDH1A1PARP1ERCC1 | |
| SCHEMBL7977895 | 0.86 | SIRT2 (0.61) | SIRT2SIRT1SLC2A1SIRT3TARBP2 | |
| SCHEMBL7977730 | 0.80 | SIRT2 (0.50) | SIRT2SIRT1SIRT3TARBP2ALDH1A1 | |
| SCHEMBL7991809 | 0.80 | SIRT2 (0.59) | SIRT2SIRT1SIRT3TARBP2KDM4E | |
| SCHEMBL7991839 | 0.80 | SIRT2 (0.50) | SIRT2SIRT1SIRT3TARBP2ALDH1A1 | |
| SCHEMBL7991536 | 0.80 | SIRT2 (0.52) | SIRT2SIRT1SLC2A1SIRT3TARBP2 | |
| SCHEMBL7989667 | 0.79 | SIRT2 (0.61) | SIRT2SIRT1SIRT3TARBP2KDM4E | |
| SCHEMBL7977903 | 0.79 | AURKA (0.49) | ALDH1A1KDM4EMEN1LMNAMAPT | |
| SCHEMBL7977992 | 0.78 | SIRT2 (0.46) | SIRT2SIRT1SLC2A1SIRT3TARBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |