Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.48 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989055 | 0.92 | SIRT2 (0.46) | SLC2A1PARP1ERCC1FEN1ERCC4 | |
| SCHEMBL7977895 | 0.88 | SIRT2 (0.61) | SLC2A1PARP1SIRT2SIRT1ALOX5 | |
| SCHEMBL7988555 | 0.86 | PARP1 (0.54) | PARP1ERCC1FEN1ERCC4ALOX5 | |
| SCHEMBL7991809 | 0.82 | SIRT2 (0.59) | SIRT2SIRT1ALOX5RAB9AMAPT | |
| SCHEMBL7991536 | 0.82 | SIRT2 (0.52) | SLC2A1SIRT2SIRT1ALOX5LMNA | |
| SCHEMBL7989667 | 0.81 | SIRT2 (0.61) | SIRT2SIRT1ALOX5RAB9AMAPT | |
| SCHEMBL7977730 | 0.80 | SIRT2 (0.50) | SIRT2SIRT1ALOX5MAPTSMN1; SMN2 | |
| SCHEMBL7990035 | 0.80 | SIRT2 (0.46) | SIRT2SIRT1ALOX5RAB9AMAPT | |
| SCHEMBL7989599 | 0.80 | SIRT2 (0.52) | PARP1ERCC1FEN1ERCC4SIRT2 | |
| SCHEMBL7989731 | 0.80 | SIRT2 (0.49) | SIRT2SIRT1ALOX5RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |