Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988176 | 0.99 | ALDH1A1 (0.44) | GAAMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL7978052 | 0.93 | PARP1 (0.46) | GAAMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL7977735 | 0.91 | LMNA (0.50) | GAAMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL7989878 | 0.91 | GAA (0.49) | GAAMEN1KMT2ANPC1MGAM | |
| SCHEMBL7977964 | 0.90 | LMNA (0.49) | GAAMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL7989394 | 0.88 | KMT2A (0.53) | GAAMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL7995795 | 0.88 | KMT2A (0.52) | GAAMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL7977725 | 0.88 | FGFR1 (0.42) | GAAMEN1ALDH1A1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL7977674 | 0.87 | KMT2A (0.51) | GAAMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL7988131 | 0.87 | KDM4E (0.41) | GAAMEN1ALDH1A1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |