Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977884 | 0.89 | SIRT2 (0.56) | RAB9AMAPK1POLBTSHRMEN1 | |
| SCHEMBL7992083 | 0.83 | RAB9A (0.50) | RAB9AMAPK1POLBTSHRMEN1 | |
| SCHEMBL7977513 | 0.83 | MEN1 (0.54) | RAB9AMAPK1POLBTSHRMEN1 | |
| SCHEMBL7995070 | 0.83 | MEN1 (0.54) | RAB9AMAPK1POLBTSHRMEN1 | |
| SCHEMBL7989403 | 0.82 | AURKA (0.51) | RAB9AMAPK1POLBTSHRMEN1 | |
| SCHEMBL7977950 | 0.82 | MAPT (0.53) | RAB9AMAPK1POLBTSHRMEN1 | |
| Hydrochloric Acid SCHEMBL7977943 | 0.82 | MEN1 (0.53) | RAB9AMAPK1POLBTSHRMEN1 | |
| SCHEMBL6707244 | 0.81 | RAB9A (0.48) | RAB9AMAPK1POLBTSHRMEN1 | |
| SCHEMBL7977957 | 0.80 | TOP2A (0.51) | RAB9AMAPK1POLBMEN1KMT2A | |
| SCHEMBL7977876 | 0.80 | MEN1 (0.51) | RAB9AMAPK1POLBTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |