Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1879943 | 0.88 | MAPT (0.49) | HTTMAPTESR2NR1H2KMT2A | |
| SCHEMBL7988759 | 0.86 | KMT2A (0.50) | HTTGAAMAPTESR2NR1H2 | |
| SCHEMBL7992678 | 0.83 | ITGB3 (0.45) | HTTGAAMAPTKMT2AALDH1A1 | |
| SCHEMBL5778678 | 0.83 | MAPT (0.47) | MAPTESR2NR1H2KMT2AALDH1A1 | |
| SCHEMBL20792550 | 0.82 | MAPT (0.56) | MAPTESR2NR1H2ALDH1A1TSHR | |
| SCHEMBL16217165 | 0.81 | MAPT (0.54) | MAPTESR2NR1H2PDK2MAPK1 | |
| SCHEMBL16379671 | 0.80 | MAPT (0.53) | HTTMAPTESR2NR1H2PDK2 | |
| SCHEMBL16220604 | 0.80 | MAPT (0.53) | MAPTESR2NR1H2PDK2MAPK1 | |
| SCHEMBL30915383 | 0.79 | MAPT (0.54) | HTTMAPTESR2NR1H2ALDH1A1 | |
| SCHEMBL6893628 | 0.78 | NR1H2 (0.40) | HTTGAAMAPTESR2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |