Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 3/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984721 | 1.00 | MAPT (0.43) | MAPTSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL7985549 | 1.00 | MAPT (0.43) | MAPTSMN1; SMN2NPC1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL7980991 | 0.98 | MAPT (0.42) | MAPTSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL7985616 | 0.93 | MAPT (0.47) | MAPTSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL7985025 | 0.83 | MAPK1 (0.44) | MAPTSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL5671427 | 0.81 | NOS3 (0.43) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL6993351 | 0.81 | NOS3 (0.42) | SMN1; SMN2MEN1KMT2AMAPK1NOS3 | |
| Hydrochloric Acid SCHEMBL6996690 | 0.80 | NOS3 (0.44) | SMN1; SMN2MEN1KMT2AMAPK1NOS3 | |
| SCHEMBL7002475 | 0.78 | NOS3 (0.55) | NOS3NOS1NOS2CYP3A4 | |
| Hydrochloric Acid SCHEMBL7004141 | 0.77 | NOS1 (0.57) | NOS3NOS1NOS2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191127-B1 | ANTIINFLAMMATORY AGENTS, AUTOIMMUNE DISEASES, CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |