Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 8/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975233 | 0.86 | ALOX5 (0.47) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL13021506 | 0.79 | MAOB (0.56) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL24448850 | 0.76 | ALOX5 (0.51) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL21617280 | 0.76 | MAOB (0.53) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL10390637 | 0.73 | CYP1A2 (0.44) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL27922861 | 0.73 | CYP1A2 (0.55) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL17481249 | 0.73 | ALOX5 (0.51) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL6825691 | 0.72 | MAOB (0.52) | ALOX5MAOB | |
| SCHEMBL11974257 | 0.71 | MAOB (0.57) | ALOX5LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL6405256 | 0.71 | LMNA (0.56) | LMNACYP1A2PTGS1SLC6A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |