Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989409 | 1.00 | DRD4 (0.44) | DRD4SIGMAR1DRD2HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL7986142 | 0.99 | DRD4 (0.43) | DRD4SIGMAR1DRD2HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL7986140 | 0.99 | DRD4 (0.43) | DRD4SIGMAR1DRD2HTR2AHTR2C | |
| SCHEMBL7972507 | 0.95 | SIGMAR1 (0.46) | DRD4SIGMAR1DRD2HTR2AHTR2C | |
| SCHEMBL7972512 | 0.95 | SIGMAR1 (0.46) | DRD4SIGMAR1DRD2HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL7982947 | 0.94 | SIGMAR1 (0.45) | DRD4SIGMAR1DRD2HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL7982951 | 0.94 | SIGMAR1 (0.45) | DRD4SIGMAR1DRD2HTR2AHTR2C | |
| SCHEMBL7986125 | 0.89 | LTA4H (0.44) | MAOAMAOBALDH1A1BLM | |
| SCHEMBL7971710 | 0.89 | LTA4H (0.44) | MAOAMAOBALDH1A1BLM | |
| Hydrochloric Acid SCHEMBL7984715 | 0.88 | LTA4H (0.43) | HTR2AMAOAMAOBALDH1A1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |