Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986303 | 0.84 | CYP1A2 (0.43) | CYP1A2RAB9ANPC1SLC1A3S1PR3 | |
| SCHEMBL7975142 | 0.83 | HPGD (0.32) | S1PR3ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL7989518 | 0.82 | CYP1A2 (0.41) | CYP1A2RAB9ANPC1NPSR1SLC1A3 | |
| SCHEMBL7988545 | 0.80 | SLC1A3 (0.41) | CYP1A2RAB9ANPC1SLC1A3S1PR3 | |
| SCHEMBL7989160 | 0.77 | KDM4E (0.40) | CYP1A2RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL7986786 | 0.76 | — | — | |
| SCHEMBL7992358 | 0.75 | HPGD (0.44) | CYP1A2RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL7992609 | 0.75 | CCNE1 (0.37) | CYP1A2RAB9ANPC1SLC1A3S1PR3 | |
| SCHEMBL7985688 | 0.73 | RAB9A (0.46) | CYP1A2RAB9ANPC1NPSR1ALDH1A1 | |
| SCHEMBL20118384 | 0.72 | SLC1A3 (0.44) | CYP1A2RAB9ANPC1SLC1A3S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |