Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991985 | 0.91 | SMN1; SMN2 (0.46) | RAB9ANPC1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL7988044 | 0.89 | NPC1 (0.47) | RAB9ANPC1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL7992142 | 0.88 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL7988275 | 0.85 | MAPT (0.48) | RAB9ANPC1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL7989229 | 0.85 | MEN1 (0.56) | RAB9ANPC1SMN1; SMN2L3MBTL1AURKA | |
| SCHEMBL7977897 | 0.83 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL7991845 | 0.82 | SMN1; SMN2 (0.44) | RAB9ANPC1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL7995060 | 0.82 | COMT (0.47) | RAB9ANPC1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL7989018 | 0.80 | MAPT (0.47) | RAB9ANPC1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL7991736 | 0.79 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2AURKAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |