Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27819169 | 0.94 | POLB (0.46) | POLBGAANPSR1PRKCAALDH1A1 | |
| SCHEMBL29049106 | 0.92 | POLB (0.44) | POLBGAANPSR1PRKCAALDH1A1 | |
| SCHEMBL3204409 | 0.91 | ALDH1A1 (0.54) | POLBGAANPSR1PRKCAALDH1A1 | |
| SCHEMBL4156534 | 0.91 | POLB (0.41) | POLBGAANPSR1PRKCAALDH1A1 | |
| SCHEMBL23837105 | 0.89 | POLB (0.40) | POLBGAANPSR1PRKCAALDH1A1 | |
| SCHEMBL4258156 | 0.88 | POLB (0.48) | POLBGAANPSR1PRKCAALDH1A1 | |
| SCHEMBL2531853 | 0.87 | CYP4F2 (0.47) | POLBGAANPSR1PRKCAALDH1A1 | |
| SCHEMBL126843 | 0.87 | ALDH1A1 (0.56) | POLBGAANPSR1ALDH1A1ATM | |
| SCHEMBL2531851 | 0.87 | POLB (0.42) | POLBGAANPSR1PRKCAALDH1A1 | |
| SCHEMBL24090907 | 0.87 | CYP4F2 (0.43) | POLBGAANPSR1PRKCAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102164933-A | Process for preparing mono-carboxy-functionalized dialkylphosphinic acids, esters and salts by means of alkylene oxides and use thereof | CLARIANT INT LTD | 2011-08-24 | — | — | CN | disclosed |
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |