Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.41 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5780615 | 0.91 | ALDH1A1 (0.50) | ALDH1A1CHRM5CHRM1CHRM3PGR | |
| SCHEMBL7989588 | 0.91 | POLB (0.46) | ALDH1A1TSHRGAAPOLBNPSR1 | |
| SCHEMBL27819169 | 0.85 | POLB (0.46) | ALDH1A1TSHRGAAPOLBNPSR1 | |
| SCHEMBL29049106 | 0.83 | POLB (0.44) | ALDH1A1TSHRGAAPOLBNPSR1 | |
| SCHEMBL315271 | 0.83 | ALDH1A1 (0.74) | ALDH1A1CHRM5CHRM1CHRM3PGR | |
| SCHEMBL4156534 | 0.82 | POLB (0.41) | ALDH1A1TSHRGAAPOLBNPSR1 | |
| SCHEMBL12083053 | 0.81 | ALDH1A1 (0.54) | ALDH1A1CHRM5CHRM1CHRM3PGR | |
| SCHEMBL15196261 | 0.81 | ALDH1A1 (0.48) | ALDH1A1CHRM5CHRM1CHRM3PGR | |
| SCHEMBL23837105 | 0.80 | POLB (0.40) | ALDH1A1GAAPOLBNPSR1PRKCA | |
| SCHEMBL16185832 | 0.80 | GAA (0.40) | ALDH1A1TSHRGAAPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4708955-A | ANTIBACTERIALS | BRISTOL-MYERS COMPANY (US) | 1987-11-24 | — | — | US | claimed |
| US-7683211-B2 | Jasmonate derivative compounds pharmaceutical compounds and methods of use thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2010-03-23 | — | — | US | disclosed |
| US-20080319066-A1 | Jasmonate Derivative Compounds, Pharmaceuticals Compounds and Methods of Use Thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2008-12-25 | — | — | US | disclosed |
| US-20080281105-A1 | Novel Quinolinium Salts and Derivatives | IMMUSOL INCORPORATED (US) | 2008-11-13 | — | — | US | disclosed |
| US-20080274998-A1 | Disaccharide Molecules and Derivatives Thereof and Methods of Using Same | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2008-11-06 | — | — | US | disclosed |
| US-7425651-B2 | Jasmonate derivative compounds, pharmaceuticals compounds and methods of use thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2008-09-16 | — | — | US | disclosed |
| US-20070142474-A1 | Jasmonate derivative compounds, pharmaceuticals compounds and methods of use thereof | VIDAC PHARMA LTD. (IL) | 2007-06-21 | — | — | US | disclosed |
| EP-1689696-A2 | JASMONATE DERIVATIVE COMPOUNDS, PHARMACEUTICALS COMPOSITIONS AND METHODS OF USE THEREOF | Ramot at Tel-Aviv University Ltd. (IL) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005076743-A2 | DISACCHARIDE MOLECULES AND DERIVATIVES THEREOF AND METHODS OF USING SAME | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2005-08-25 | — | — | WO | disclosed |
| WO-2005054172-A2 | JASMONATE DERIVATIVE COMPOUNDS, PHARMACEUTICALS COMPOSITIONS AND METHODS OF USE THEREOF | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2005-06-16 | — | — | WO | disclosed |
| WO-2001014879-A1 | 4-UNSUBSTITUTED DIHYDROISOQUINOLINONE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-03-01 | — | — | WO | disclosed |
| WO-2001000594-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-01-04 | — | — | WO | disclosed |
| WO-2000045635-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2000-08-10 | — | — | WO | disclosed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | disclosed |
| EP-0863877-A4 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INST (US) | 1999-07-21 | — | — | EP | disclosed |
| EP-0863877-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997016428-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1997-05-09 | — | — | WO | disclosed |
| EP-0451764-A1 | Carbapenem compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1991-10-16 | — | — | EP | disclosed |
| EP-0421751-A2 | Substituted acrylamido-penicillanic acid esters | Beecham Group p.l.c. (GB) | 1991-04-10 | — | — | EP | disclosed |
| EP-0409081-A1 | Beta-Lactam Derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080274998-A1 | Disaccharide Molecules and Derivatives Thereof and Methods of Using Same | MSN, MAN2B2, MASP2 | ALDH1A1 4079/4885CHRM5 1403/4885CHRM1 2606/4885 |
| US-20070142474-A1 | Jasmonate derivative compounds, pharmaceuticals compounds and methods of use thereof | BCL6, GGPS1, FDPS | ALDH1A1 3349/4885CHRM5 2611/4885CHRM1 3680/4885 |
| US-20080281105-A1 | Novel Quinolinium Salts and Derivatives | NQO2, MCL1, KRAS | ALDH1A1 3206/4885CHRM5 3756/4885CHRM1 3383/4885 |
| US-20080319066-A1 | Jasmonate Derivative Compounds, Pharmaceuticals Compounds and Methods of Use Thereof | BCL6, GGPS1, FDPS | ALDH1A1 3349/4885CHRM5 2611/4885CHRM1 3680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.