Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 11/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | CYP8B1 | Q9UNU6 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31454781 | 1.00 | CYP3A4 (0.44) | CYP3A4CYP2C9CYP2C19CYP19A1CYP11B1 | |
| SCHEMBL3949948 | 1.00 | CYP3A4 (0.44) | CYP3A4CYP2C9CYP2C19CYP19A1CYP11B1 | |
| SCHEMBL3264782 | 1.00 | CYP3A4 (0.44) | CYP3A4CYP2C9CYP2C19CYP19A1CYP11B1 | |
| SCHEMBL8812022 | 1.00 | CYP3A4 (0.44) | CYP3A4CYP2C9CYP2C19CYP19A1CYP11B1 | |
| SCHEMBL300482 | 1.00 | CYP3A4 (0.44) | CYP3A4CYP2C9CYP2C19CYP19A1CYP11B1 | |
| SCHEMBL2346412 | 1.00 | CYP3A4 (0.44) | CYP3A4CYP2C9CYP2C19CYP19A1CYP11B1 | |
| SCHEMBL17777817 | 1.00 | CYP3A4 (0.44) | CYP3A4CYP2C9CYP2C19CYP19A1CYP11B1 | |
| SCHEMBL8574154 | 1.00 | CYP3A4 (0.44) | CYP3A4CYP2C9CYP2C19CYP19A1CYP11B1 | |
| SCHEMBL3955770 | 1.00 | CYP3A4 (0.44) | CYP3A4CYP2C9CYP2C19CYP19A1CYP11B1 | |
| SCHEMBL29858099 | 1.00 | CYP3A4 (0.44) | CYP3A4CYP2C9CYP2C19CYP19A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756783-A | Preparation method of difluprednate | 浙江东亚药业股份有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-110997646-B | Process for producing epoxy alcohol compound | 住友化学株式会社 | 2023-06-20 | — | — | CN | disclosed |
| EP-3397628-A1 | PROCESS FOR THE SYNTHESIS OF EFINACONAZOL | Procos S.p.A. (IT) | 2018-11-07 | — | — | EP | disclosed |
| WO-2017114743-A1 | PROCESS FOR THE SYNTHESIS OF EFINACONAZOL | PROCOS S.P.A. (IT) | 2017-07-06 | — | — | WO | disclosed |
| US-20010031768-A1 | Triazole antifungal agent | SANKYO COMPANY LIMITED (JP) | 2001-10-18 | — | — | US | disclosed |
| US-5789429-A | FUNGICIDE | EISAI CO., LTD. (JP) | 1998-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031768-A1 | Triazole antifungal agent | ERG28, RIF1, NAT1 | CYP3A4 24/4885CYP2C9 491/4885CYP2C19 252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.