Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976072 | 0.87 | MAPK9 (0.52) | MAPK9KMT2AMEN1PTGS1PTGS2 | |
| SCHEMBL7986595 | 0.85 | PTGS1 (0.55) | MAPK9KMT2AMEN1PTGS1PTGS2 | |
| SCHEMBL7986479 | 0.82 | TAS1R3 (0.50) | MAPK9KMT2AMEN1PTGS1PTGS2 | |
| SCHEMBL14537417 | 0.81 | AKR1C3 (0.66) | MAPK9KMT2AMEN1PTGS1PTGS2 | |
| SCHEMBL31062585 | 0.81 | AKR1C3 (0.66) | MAPK9KMT2AMEN1PTGS1PTGS2 | |
| SCHEMBL7835310 | 0.81 | AKR1C3 (0.66) | MAPK9KMT2AMEN1PTGS1PTGS2 | |
| SCHEMBL7990464 | 0.80 | MAPK9 (0.54) | MAPK9KMT2AMEN1PTGS1PTGS2 | |
| SCHEMBL8035766 | 0.80 | PTGS1 (0.59) | MAPK9KMT2AMEN1PTGS1PTGS2 | |
| SCHEMBL7976514 | 0.80 | TAS1R3 (0.52) | MAPK9KMT2AMEN1PTGS1PTGS2 | |
| Hydrochloric Acid SCHEMBL11410387 | 0.79 | PTGS1 (0.58) | MAPK9KMT2AMEN1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207686-B1 | FOR THERAPY OF HYPERTENSION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |
| WO-1996015109-A1 | ENDOTHELIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-23 | — | — | WO | disclosed |