Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | AGXT | P21549 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7513004 | 0.88 | KMT2A (0.47) | HTTCA1CA2AGXTKMT2A | |
| SCHEMBL7505249 | 0.87 | HTT (0.43) | HTTCA1CA2KMT2AMEN1 | |
| SCHEMBL7990277 | 0.87 | HTT (0.43) | HTTCA1CA2AGXTKMT2A | |
| SCHEMBL7986938 | 0.87 | HTT (0.43) | HTTCA1CA2KMT2AMEN1 | |
| SCHEMBL7451566 | 0.87 | HTT (0.58) | HTTCA1CA2KMT2APOLB | |
| SCHEMBL7975872 | 0.85 | HTT (0.41) | HTTCA1CA2KMT2AMEN1 | |
| SCHEMBL7515208 | 0.83 | HTT (0.41) | HTTKMT2AMEN1POLBTACR1 | |
| SCHEMBL7450571 | 0.82 | HTT (0.53) | HTTCA1CA2KMT2AMEN1 | |
| SCHEMBL7976000 | 0.81 | HTT (0.50) | HTTKMT2AGAA | |
| SCHEMBL7507835 | 0.81 | LOXL2 (0.42) | HTTCA1CA2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313177-B1 | AS ANTIVIRAL AGENTS | PHARMACOR INC. (CA) | 2001-11-06 | — | — | US | disclosed |