Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | PRKCA | P17252 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5665910 | 0.83 | KMT2A (0.66) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL2861614 | 0.80 | KMT2A (0.62) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL14461612 | 0.80 | TDP1 (0.62) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL21843056 | 0.79 | ALDH1A1 (0.64) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL7990400 | 0.79 | SLC6A2 (0.51) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL7516982 | 0.78 | CA1 (0.47) | KMT2ALMNAMAPTHPGDRAB9A | |
| SCHEMBL7990473 | 0.78 | CA1 (0.47) | KMT2ALMNAMAPTHPGDRAB9A | |
| SCHEMBL4535813 | 0.78 | TDP1 (0.58) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL5742123 | 0.77 | CA1 (0.56) | KMT2AMAPK1SLC1A1 | |
| SCHEMBL7502596 | 0.77 | NR4A1 (0.49) | KMT2AALDH1A1HPGDMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313177-B1 | AS ANTIVIRAL AGENTS | PHARMACOR INC. (CA) | 2001-11-06 | — | — | US | disclosed |