Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.41 |
| ▸ | KDM1A | O60341 | 6/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | ARG1 | P05089 | 1/20 | 0.39 |
| ▸ | ARG2 | P78540 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 3/20 | 0.39 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | UBE2M | P61081 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7986552 | 0.99 | KCNH2 (0.41) | KCNH2KDM1AHDAC6LTA4HARG1 | |
| SCHEMBL7986176 | 0.92 | KCNH2 (0.46) | KCNH2LTA4HCCR3CACNA1IMAOB | |
| Hydrochloric Acid SCHEMBL7971933 | 0.92 | KCNH2 (0.46) | KCNH2LTA4HCCR3CACNA1IMAOB | |
| SCHEMBL7989275 | 0.91 | CCR3 (0.47) | KDM1AHDAC6LTA4HCCR3 | |
| SCHEMBL7983788 | 0.91 | LTA4H (0.44) | KDM1AHDAC6LTA4HCCR3CHRM4 | |
| Hydrochloric Acid SCHEMBL7986155 | 0.91 | CCR3 (0.47) | KDM1AHDAC6LTA4HCCR3 | |
| SCHEMBL7990607 | 0.91 | GRIN2B (0.41) | KCNH2KDM1AHDAC6LTA4HCCR3 | |
| SCHEMBL7982426 | 0.90 | LTA4H (0.47) | KCNH2KDM1AHDAC6LTA4HHDAC3 | |
| Hydrochloric Acid SCHEMBL7983277 | 0.90 | LTA4H (0.44) | KDM1AHDAC6LTA4HCCR3CHRM4 | |
| SCHEMBL7972913 | 0.90 | LTA4H (0.42) | KCNH2KDM1AHDAC6LTA4HCCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |