Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.46 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 3/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7971933 | 0.99 | KCNH2 (0.46) | KCNH2CACNA1IGLSALDH1A1CHRM4 | |
| SCHEMBL7989836 | 0.92 | KCNH2 (0.41) | KCNH2CACNA1ICHRM4CCR3UBE2M | |
| Hydrochloric Acid SCHEMBL7986552 | 0.92 | KCNH2 (0.41) | KCNH2CACNA1ICHRM4CCR3UBE2M | |
| SCHEMBL7983503 | 0.90 | KDM1A (0.42) | CCR3LTA4H | |
| SCHEMBL7989617 | 0.90 | PIM1 (0.43) | KCNH2GLSCHRM4CCR3CHRM2 | |
| Hydrochloric Acid SCHEMBL7981947 | 0.89 | KDM1A (0.41) | CCR3LTA4H | |
| Hydrochloric Acid SCHEMBL7982551 | 0.89 | PIM1 (0.43) | KCNH2GLSCHRM4CCR3CHRM2 | |
| SCHEMBL7982426 | 0.89 | LTA4H (0.47) | KCNH2ALDH1A1CHRM4LTA4HMAOB | |
| SCHEMBL7981938 | 0.89 | CACNA1I (0.43) | KCNH2CACNA1ILTA4H | |
| Hydrochloric Acid SCHEMBL7971795 | 0.88 | LTA4H (0.47) | KCNH2ALDH1A1CHRM4LTA4HMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |